Real Reaction: Build Bonds with Engaging Chemistry Learning

REAL Reactions

Insights and innovations for chemistry educators, sparking connections in every lesson.

“I started thinking, surely we can use technology to teach science better,” he says. “That set me down a path to creating projects that were all about using digital technologies at scale to teach science as a process.”

Ariel Anbar came to this conclusion soon after he began teaching introductory chemistry courses in the School of Molecular Sciences at Arizona State University (ASU) in 2004. 



Now Anbar is co-principal investigator of REAL CHEM, general chemistry courseware that pairs Arizona State University's Education Through Exploration (ETX) with the Open Learning Initiative (OLI) at Carnegie Mellon University. Together, they developed courseware that bridges abstract chemistry concepts with real-world applications, while maintaining essential college-level rigor.

The core instructional design principles informing REAL CHEM are built into the name—Relevant, Engaging, Active Learning. Anbar and his colleagues are committed to the idea that courseware built on those practices can benefit all students.

When chemistry clicks, confidence soars.
At REAL CHEM, we’re not just teaching science—we’re sparking joy, empowerment, and a love for learning.

11,000 students are using REAL CHEM

THE STORY OF REAL CHEM

Created in collaboration between Arizona State University and Carnegie Mellon University, REAL CHEM is designed to help educators engage, inspire, and build confidence in their general chemistry students.

Backed by years of teaching experience and learning science research, we are committed to the idea that reaching students with varying levels of academic preparation is the key to boosting their success. That’s why we developed cinematic videos that break down complex concepts, problem-solving assignments using real-world data, and active learning strategies to form the foundation of our courseware.

With over 6,000 students using REAL CHEM across 30 institutions, we’re making an impact on retention and student outcomes. When students see themselves in chemistry, they explore deeper, solve harder problems, and push their understanding further.

Let’s build bonds that last beyond the classroom.
— The REAL CHEM Team

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EDUCATOR'S CORNER

Amy E. Irwin, PhD
Chemist/OBM Dr. of Documents
Faculty Ambassador, REAL CHEM

My passion for chemistry began in high school. It wasn’t always easy, but I was fascinated by how it explained the world.

During undergrad I had my son, which made the journey harder but more meaningful. I earned a PhD in Inorganic Chemistry, completed post-doctoral research, and taught large General Chemistry courses.

I later led an Environmental Radiochemistry Lab supporting the U.S. Navy and then taught Radiochemistry and Organic Chemistry at a community college while caring for my son and ailing mother. I connected deeply with students balancing similar challenges.

After my mother passed, I joined a college in Kentucky serving first-generation students like me. I later returned to teaching in New York before moving into industry, working in quality management and systems engineering.

Chemistry taught me to adapt, write clearly, and explain complex ideas—skills that reach far beyond the lab. Now, I run my own business and am excited to be working with REAL CHEM as a faculty ambassador!

Chemistry in the News
Sparking Discussion with your Students

Green Chemistry is a branch of chemistry focused on designing and using chemicals that minimize pollution and hazardous waste. A key area of emphasis is reducing the impact of everyday chemicals used in homes and personal products.

Hypochlorous acid (HOCl) is a non-toxic, skin-safe cleaner and weak acid that’s powerful enough to kill even the most stubborn viruses, including COVID-19 and norovirus—the infamous culprit behind cruise ship outbreaks. Amazingly, our bodies naturally produce HOCl as part of the immune response when fighting infection or healing wounds.

But don’t confuse it with sodium hypochlorite, the harsh chemical found in household bleach. Why focus on hypochlorous acid? Because it’s an incredibly effective germ-killer. So why isn’t it more widely known?

As highlighted in Scientific American’s article, “The Nontoxic Cleaner That Kills Germs Better Than Bleach—And You Can Use It on Your Skin,” author Jen Schwartz explains how earlier challenges with HOCl’s stability (especially exposure to air and light) limited its use. But recent innovations have solved those issues, making it possible to safely harness this compound in everyday cleaners—for hands, kitchens, and beyond.

It’s safe, it’s effective, and it was well worth the wait.

– Amy E. Irwin, PhD

NEW!

Updates to REAL CHEM I & II Rolling Out this Fall!
Give your students a tour of the chemical world, the REAL CHEM way!

More active learning Explorations highlighting real-world applications
New comprehensive lecture slides to support in-person teaching
New deliberate practice exercises
2 new course modes: AI mode and non-AI mode

Interested in learning more about these new features?

Click here to schedule a demo with our team

JOIN US!

This summer, the Chemistry Education (CE) track at the LearnLab Summer School at Carnegie Mellon University is your chance to dive into real classroom data and advance your research skills. Perfect for educators, researchers, and learning scientists who want to explore how students learn—and contribute to meaningful, data-driven insights.

Learn more and apply here

Events
Come meet the REAL CHEM team

ChemED
July 20-25, Golden, CO
EDUCAUSE
Oct. 27-30, Nashville, TN

Get Involved with
the REAL CHEM Community

Join general chemistry faculty in MERLOT’s REAL CHEM Innovation Project for professional development and research opportunities.

Opportunities to participate include:

Chances to contribute to the development of new, evidence based general chemistry courseware

Co-authoring a presentation at the Online Learning Consortium ACCELERATE Conference (Nov 17-20, 2025) with MERLOT

Joining REAL CHEM’s community of practice, where instructors share teaching strategies and insights with educators nationwide

To learn more

Visit MERLOT Innovation Project’s website
To request a short platform demonstration
Schedule a meeting with someone from our team

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01

Unveiling the Power of Matter and Energy

  • Basic Concepts of Matter and Energy
  • Measurements
02

Unit 2: Atoms, Molecules and Ions

  • Atomic Theory and the Periodic Table
  • Compounds and Chemical Formulas
  • Exploration: Do you really want to drink that? The elements of water.
03

Electronic Structure and Periodic Properties

  • Electromagnetic Energy and the Bohr Model of the Atom
  • Quantum Theory
  • Periodic Properties
  • Exploration: What’s the World Made Of? Unlocking Secrets with Spectroscopy
04

Chemical Bonding and Molecular Geometry

  • Ionic and Covalent Bonding
  • Lewis Structures
  • Molecular Structure and Polarity
  • Advanced Theories of Covalent Bonding
  • Exploration: Decoding the Mystery of Greenhouse Molecules
05

Composition
of Substances

  • Mole Calculations
  • Aqueous Solutions
  • Exploration: Is the Town Toxic? Quantifying Concentrations of Lead.
06

Reactions and
Stoichiometry

  • Chemical Reactions and Equations
  • Chemical Reactions Stoichiometry
  • Exploration: Driving Down Greenhouse Emissions
07

Gases

  • Gas Laws
  • Stoichiometry of Gases
  • The Kinetic-Molecular Theory
08

Thermochemistry

  • Introduction to Energy
  • Calorimetry
  • Enthalpy
  • Exploration: What’s Our Next Big Energy Source?
09

Liquids and Solids

  • Intermolecular Forces
  • Phase Changes
  • The Solid State of Matter
10

Solutions

  • Solubility
  • Colligative Properties

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